ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity
The findings of our research indicate that ZXYF exerts a defensive role in the advancement of AS. The mechanism underlying the role of ZXYF in combating AS is closely associated with gut microbiota reshaping and regulation of enterohepatic bile acid circulation.
Authors
- Shihan Zhou (ORCID: https://orcid.org/0000-0002-9304-5480)
- Xinyu Yang (ORCID: https://orcid.org/0000-0001-5498-1877)
- Yan-Qing Wang
- Boran Zhu (ORCID: https://orcid.org/0000-0002-4894-150X)
- Haoxin Wu (ORCID: https://orcid.org/0000-0001-5767-408X)
- Min Ni (ORCID: https://orcid.org/0000-0002-4587-1622)
- Jing Liu (ORCID: https://orcid.org/0000-0002-3113-4015)
- Xinyi Chen (ORCID: https://orcid.org/0000-0002-6822-0806)
- Anwei Ding (ORCID: https://orcid.org/0000-0003-1839-6579)
- Zizhen Qin
- Wanning Wu
- Shao‐Ying Hua
- Xiaowei Chen (ORCID: https://orcid.org/0000-0001-5420-1359)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Traditional Chinese Medicine Hospital of Kunshan (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-05-25
- DOI
- https://doi.org/10.1186/s13020-025-01116-y
- Citations
- 6
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.84