Gankyrin Inhibition Can Control <scp><i>Helicobacter pylori</i></scp> Generated Gastric Cancer Using In Vivo Xenograft Models
These findings suggest that Gankyrin plays a crucial role in H. pylori-mediated GC progression by modulating inflammatory and tumor suppressor pathways. Targeting Gankyrin could provide a therapeutic strategy to mitigate the development of GC associated with H. pylori infection.
Authors
- Hem Chandra Jha (ORCID: https://orcid.org/0000-0002-9698-4547)
- Tarun Verma (ORCID: https://orcid.org/0000-0003-3937-2111)
- Hamendra Singh Parmar (ORCID: https://orcid.org/0000-0002-9866-2760)
- Nidhi Varshney (ORCID: https://orcid.org/0000-0002-6798-6703)
- Pranit Hemant Bagde (ORCID: https://orcid.org/0000-0002-9703-1051)
- Siddharth Singh (ORCID: https://orcid.org/0000-0002-1388-6221)
- Dharmendra K. Kashyap (ORCID: https://orcid.org/0000-0003-3871-0166)
- Anamika Singh (ORCID: https://orcid.org/0000-0001-7394-5687)
Institutions
- Devi Ahilya Vishwavidyalaya (IN)
- Indian Institute of Technology Indore (IN)
Publication Details
- Journal
- Helicobacter
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1111/hel.70046
- Citations
- 1
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Department of Science and Technology, Ministry of Science and Technology, India
- Indian Council of Medical Research
- Science and Engineering Research Board