Combination of Cpb-Hsp70 typing methods reveals genetic divergence between Leishmania infantum strains causing human tegumentary leishmaniasis in northern Italy and central Spain: a retrospective study
Our findings show differences among L. infantum populations causing TL in two southern European epidemiological foci of human leishmaniasis and support the recent discovery of L. infantum/L.donovani hybrid strains circulating in northern Italy. These results underscore the critical need to identify the circulating Leishmania strains in endemic areas and assess their potential public health implications in active foci.
Authors
- Tommaso Gritti (ORCID: https://orcid.org/0000-0001-5473-6070)
- Eugenia Carrillo (ORCID: https://orcid.org/0000-0002-7869-7915)
- Tiziana Lazzarotto (ORCID: https://orcid.org/0000-0003-3093-363X)
- Sara Morselli (ORCID: https://orcid.org/0000-0002-8400-0467)
- José Carlos Solana (ORCID: https://orcid.org/0000-0002-0485-6127)
- Javier Moreno (ORCID: https://orcid.org/0000-0003-0087-4659)
- Carmen Chicharro (ORCID: https://orcid.org/0000-0003-1297-1376)
- Gianluca Rugna (ORCID: https://orcid.org/0000-0001-7437-1929)
- Elena Carra (ORCID: https://orcid.org/0000-0002-8426-4569)
- Valeria Gaspari (ORCID: https://orcid.org/0000-0001-9712-7910)
- Stefania Varani (ORCID: https://orcid.org/0000-0003-0862-4937)
- Margherita Ortalli (ORCID: https://orcid.org/0000-0001-5447-8817)
- M. Zanazzi
Institutions
- Instituto de Salud Carlos III (ES)
- Centro de Investigación Biomédica en Red (ES)
- Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna "Bruno Ubertini" (IT)
- Azienda USL di Bologna (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Infectious Diseases of Poverty
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s40249-025-01309-5
- Citations
- 4
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 7.51
Funders
- Ministero della Salute
- Instituto de Salud Carlos III