Integrated Early CRP Kinetics and Plasma EBV DNA Clearance as Prognostic Biomarkers in De Novo Metastatic Nasopharyngeal Carcinoma Treated with First-Line Chemoimmunotherapy
CRP responders are associated with improved survival outcomes, particularly in patients achieving early EBV DNA clearance. Early CRP kinetics combined with early plasma EBV DNA clearance may be predictive of survival outcomes in dmNPC patients receiving first-line chemoimmunotherapy.
Authors
- Hao Zhang (ORCID: https://orcid.org/0000-0001-5973-7080)
- Tianzhu Lu (ORCID: https://orcid.org/0000-0002-1524-7909)
- Chuanmiao Xie (ORCID: https://orcid.org/0000-0001-8533-623X)
- Min Fang (ORCID: https://orcid.org/0000-0001-6688-437X)
- Yong Su (ORCID: https://orcid.org/0000-0002-8888-8694)
- Tiejun Wang (ORCID: https://orcid.org/0000-0002-2362-8007)
- Xiaochang Gong
- Yujun Hu
- Jingao Li (ORCID: https://orcid.org/0000-0002-0389-7576)
Institutions
- Nanchang University (CN)
- Sun Yat-sen University (CN)
- Jiangxi Provincial Cancer Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
- Hubei Cancer Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/jir.s512808
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangxi Province
- Chinese Academy of Medical Sciences