Population Pharmacokinetics of Tranexamic Acid in Chinese Population Undergoing Cardiac Surgery with Cardiopulmonary Bypass
This study provides the first population PK model of TXA in the Chinese population undergoing cardiac surgery with CPB. The model could serve as a reference for the future development of individualized TXA administration strategies, with target-controlled infusion (TCI) emerging as a viable option.
Authors
- Chenghui Zhou (ORCID: https://orcid.org/0000-0001-6428-6069)
- Yue Liu (ORCID: https://orcid.org/0000-0001-7408-8904)
- Jia Shi (ORCID: https://orcid.org/0000-0001-5786-895X)
- Hong Lv (ORCID: https://orcid.org/0000-0002-2334-5138)
- Lei Tian (ORCID: https://orcid.org/0009-0006-8951-1844)
- Juanjuan Jiang (ORCID: https://orcid.org/0000-0001-6131-8694)
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Anzhen Hospital (CN)
- Fu Wai Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/dddt.s493485
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science and Technology Major Project