Automated detection of free monoclonal light chains by enhanced-sensitivity modified immunofixation electrophoresis with antisera against free light chains
The automated protocol employing the SPIFE Nexus instrument and incorporating antisera to free light chains is suitable for routine use in clinical laboratories in an automated, enhanced-sensitivity assay for monoclonal light chains with no need for manual manipulation.
Authors
- Roni J. Bollag (ORCID: https://orcid.org/0000-0003-4963-6619)
- Jeff A. Spencer
- Erick Saldaña (ORCID: https://orcid.org/0000-0002-4018-2852)
- Gurmukh Singh (ORCID: https://orcid.org/0000-0003-0621-7254)
Institutions
- Augusta University (US)
- St. Helena Hospital (US)
Publication Details
- Journal
- Laboratory Medicine
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1093/labmed/lmaf014
- Citations
- 2
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.54