Performance Evaluation of a Custom-Designed Contrast Media Injector in a 5-Tesla MRI Environment

The compatibility and safety of contrast media injectors (CMIs) at ultra-high magnetic field strengths remains a critical challenge. This study aimed to investigate a custom-designed CMI powered by a ceramic motor in a newly developed 5T MRI environment, comparing it with a commercial CMI commonly used in a clinic. Three key performance aspects of the CMI were assessed in the 5T environment: translational attraction force, injection flow rates, and total injected volume. Potential imaging artifacts were checked. The custom-designed CMI demonstrated robust performance in the 5T environment, maintaining injection accuracy across all test locations and ensuring translational attraction forces remained within safe thresholds, even in the most challenging positions. Importantly, the custom-designed CMI exhibited no significant radiofrequency (RF) interference, and no imaging artifacts were observed across routine clinical sequences. In contrast, the commercial 3T CMI showed RF interference in several sensitive tests, such as the gradient echo (GRE) sequence with a 0° flip angle and frequency-based detection methods, underscoring the need for field-specific CMI designs tailored to ultra-high field environments. Further tests were performed in monkey livers and a human brain in vivo. The custom-designed CMI proved to be safe, accurate, and fully compatible with the 5T environment.

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Publication Details

Journal
Bioengineering
Published
2025-05-25
DOI
https://doi.org/10.3390/bioengineering12060566
Citations
1
Primary Topic
Advanced MRI Techniques and Applications
Type
article
Field-Weighted Citation Impact
1.36

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Performance Evaluation of a Custom-Designed Contrast Media Injector in a 5-Tesla MRI Environment

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1 citations
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Performance Evaluation of a Custom-Designed Contrast Media Injector in a 5-Tesla MRI Environment

Haibo Xu, Daniel Topgaard, Yuannan Hu, Zhusha Wang, Zhao Ruan, Rufang Liao, Wei Wang, Huan Li, Wenbo Sun
article en
1 citations

Abstract

The compatibility and safety of contrast media injectors (CMIs) at ultra-high magnetic field strengths remains a critical challenge. This study aimed to investigate a custom-designed CMI powered by a ceramic motor in a newly developed 5T MRI environment, comparing it with a commercial CMI commonly used in a clinic. Three key performance aspects of the CMI were assessed in the 5T environment: translational attraction force, injection flow rates, and total injected volume. Potential imaging artifacts were checked. The custom-designed CMI demonstrated robust performance in the 5T environment, maintaining injection accuracy across all test locations and ensuring translational attraction forces remained within safe thresholds, even in the most challenging positions. Importantly, the custom-designed CMI exhibited no significant radiofrequency (RF) interference, and no imaging artifacts were observed across routine clinical sequences. In contrast, the commercial 3T CMI showed RF interference in several sensitive tests, such as the gradient echo (GRE) sequence with a 0° flip angle and frequency-based detection methods, underscoring the need for field-specific CMI designs tailored to ultra-high field environments. Further tests were performed in monkey livers and a human brain in vivo. The custom-designed CMI proved to be safe, accurate, and fully compatible with the 5T environment.

BioengineeringVol. 12(6)
Lund University (SE), Wuhan University (CN), Zhongnan Hospital of Wuhan University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 20%
Advanced MRI Techniques and Applications
1.36
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