Dermoscopy of Solitary Multinucleate Cell Angiohistiocytoma: A Rare Amelanotic Clinical Imitator of Melanoma
Multinucleate cell angiohistiocytoma (MCAH) is a rarely reported and likely underdiagnosed cutaneous entity with benign biological behavior. MCAH is described as a solitary or multiple proliferation of vascular and fibrohistiocytic origin, with largely unknown etiopathogenesis. It presents as red-brown to violaceous papules or nodules, mainly on the extremities, and is usually asymptomatic. A definitive diagnosis of MCAH requires specific histopathological and immunohistochemical findings. The following report presents a case of solitary MCAH with the aim of clarifying the clinical, histological, and especially dermoscopic aspects of this dermatological disorder, which may resemble more aggressive skin tumors.
Authors
- Zannis Almpanis
- Dimitrios Sgouros (ORCID: https://orcid.org/0000-0003-0009-8821)
- George E. Sarris (ORCID: https://orcid.org/0000-0002-9341-2850)
- Zoé Apalla (ORCID: https://orcid.org/0000-0002-9255-8196)
Institutions
- Piedmont Athens Regional (US)
- National and Kapodistrian University of Athens (GR)
- Aristotle University of Thessaloniki (GR)
- University General Hospital Attikon (GR)
Publication Details
- Journal
- Cureus
- Published
- 2025-05-25
- DOI
- https://doi.org/10.7759/cureus.84796
- Primary Topic
- Cutaneous lymphoproliferative disorders research
- Type
- article
- Field-Weighted Citation Impact
- 0.00