Bladder cancer biomarker analysis and drugtarget prediction based on pyroptosis-related genes
This study elucidated the relationship between the development of BC and mechanisms of cellular senescence, apoptosis, and immunity. It clarified the roles of 27 genes associated with cellular senescence in BC and predicted that Triethyl phosphate, Regorafenib, Ponatinib, Lenvatinib, Nintedanib, and Quercetin may be key drugs or compounds for the treatment of BC.
Authors
- Zhumei Luo (ORCID: https://orcid.org/0000-0001-7428-9853)
- Hanchao Zhang (ORCID: https://orcid.org/0000-0001-5285-2668)
- Qin Liu (ORCID: https://orcid.org/0000-0001-9839-8480)
- Ping Li
- Xuexi Yang
Institutions
- Southwest Medical University (CN)
- Third People's Hospital of Chengdu (CN)
- Chengdu University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-25
- DOI
- https://doi.org/10.1007/s12672-025-02754-2
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56