4D flow MRI-based grading of left ventricular diastolic dysfunction: a validation study against echocardiography

Question The lack of comparison studies with echocardiography currently limits cardiac MRI-based grading of diastolic dysfunction. Could 4D flow MRI serve as a viable technique? Findings A single 4D flow MRI measurement allows multiparametric grading of left ventricular diastolic dysfunction in nearly perfect agreement with echocardiography. Clinical relevance Agreement between 4D flow MRI and echocardiographic grading of left ventricular diastolic dysfunction is comparable to that observed in repeated echocardiographic evaluations, suggesting 4D flow as a viable alternative to echocardiography in selected patients, especially when comprehensive MRI is already performed.