Excellent survival benefit achieved in patients with advanced-stage non-small cell lung cancer harboring the epidermal growth factor receptor-G719X mutation treated by afatinib: the real-world data from a multicenter study in Vietnam

Patients with the EGFR-G719X mutation achieve significantly better TTF and OS benefits than those with other uncommon EGFR mutations.

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Publication Details

Journal
Therapeutic Advances in Respiratory Disease
Published
2025-01-01
DOI
https://doi.org/10.1177/17534666251341747
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
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article

Excellent survival benefit achieved in patients with advanced-stage non-small cell lung cancer harboring the epidermal growth factor receptor-G719X mutation treated by afatinib: the real-world data from a multicenter study in Vietnam

Le Huy Trinh, Ha Thanh Vu, Văn Luận Phạm, Minh‐Hai Nguyen et al.
Therapeutic Advances in Respiratory Disease
Lung Cancer Treatments and Mutations
article

Excellent survival benefit achieved in patients with advanced-stage non-small cell lung cancer harboring the epidermal growth factor receptor-G719X mutation treated by afatinib: the real-world data from a multicenter study in Vietnam

Le Huy Trinh, Ha Thanh Vu, Văn Luận Phạm, Minh‐Hai Nguyen, Lê Anh Tuấn, Thi Bich Phuong Nguyen, Thi Thai Hoa Nguyen, Cong Minh Truong, Thi Oanh Nguyen, Van Thai Pham, Kien Hung, Tuan Khoi Nguyen, Thi Thuy Hang Nguyen, Thị Anh Thư Hoàng, Cẩm Phương Phạm, Tran Minh Chau Pham, Dac Nhan Tam Nguyen, Văn Khiêm Đặng, Đình Thy Hảo Vương, Hoang Gia Nguyen
article en

Abstract

Patients with the EGFR-G719X mutation achieve significantly better TTF and OS benefits than those with other uncommon EGFR mutations.

Therapeutic Advances in Respiratory DiseaseVol. 19
Vietnam National University, Hanoi (VN), Hanoi Medical University (VN), Cho Ray Hospital (VN), HCMC Hospital of Dermato Venereology (VN), Vietnam National Children's Hospital (VN), VinUniversity (VN), Bạch Mai Hospital (VN), 108 Military Central Hospital (VN), Hanoi Lung Hospital (VN)
Good health and well-being
Openalex Percentile: Top 81%
Lung Cancer Treatments and Mutations
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Excellent survival benefit achieved in patients with advanced-stage non-small cell lung cancer harboring the epidermal growth factor receptor-G719X mutation treated by afatinib: the real-world data from a multicenter study in Vietnam — Le Huy Trinh, Ha Thanh Vu, et al. · Therapeutic Advances in Respiratory Disease (2025) | TGRS Research Map | TGRS