Development of a Highly Active Catalyst System with Tuneable Selectivity for the Hydroformylation of the Renewable 1,3‐Diene β‐Myrcene

Abstract This study presents an optimized method for the hydroformylation of β‐myrcene using a Rh/dppe catalyst system, achieving the highest activity reported for conjugated 1,3‐dienes. By adapting conditions from hydroaminomethylation and systematically optimizing reaction parameters, the study achieves turnover frequencies of 9590 h −1 , surpassing prior reports by an order of magnitude. Key findings include the importance of controlling reaction temperature to balance activity and selectivity between primary and subsequent products. The work challenges the notion that hydroformylation of 1,3‐dienes is inherently slow and thereby not suitable for industrial application.