Astrocytic Inducible Nitric Oxide Synthase Upregulation Contributes to Chronic Below‐Level Neuropathic Pain Following Spinal Cord Injury in Male Rats

iNOS inhibition effectively alleviated pain without motor side effects, unlike non-selective NOS, nNOS and eNOS inhibitors. The colocalization of iNOS with astrocytes in the spinal cord suggests a key mechanism in pain maintenance. These findings highlight the potential of targeting iNOS as a therapeutic strategy for SCI-induced neuropathic pain with reduced risks of side effects.