Celiac Disease and Incident Dupuytren’s Contracture: A Matched Nationwide Cohort Analysis
This study explored the association between celiac disease (CeD) and Dupuytren's contracture (DC) using data from the Swedish ESPRESSO cohort. We analyzed 49,699 CeD patients and 245,267 matched controls, identifying 1420 incident DC cases. CeD patients had a 1.21-fold increased risk of DC compared to controls, with a more pronounced risk in women and older individuals. Further research is needed to understand the underlying mechanisms of this relationship.
Authors
- Daniel A. Leffler (ORCID: https://orcid.org/0000-0002-0750-3386)
- Dominic Furniss (ORCID: https://orcid.org/0000-0003-2780-7173)
- Jonas Filip Ludvigsson (ORCID: https://orcid.org/0000-0003-1024-5602)
- Susanna C. Larsson (ORCID: https://orcid.org/0000-0003-0118-0341)
- Shuai Yuan (ORCID: https://orcid.org/0000-0003-2710-286X)
Institutions
- Uppsala University (SE)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Columbia University Irving Medical Center (US)
- Nuffield Orthopaedic Centre (GB)
- Karolinska Institutet (SE)
- University of Oxford (GB)
- Örebro University Hospital (SE)
Publication Details
- Journal
- Clinical Epidemiology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/clep.s518939
- Citations
- 1
- Primary Topic
- Dupuytren's Contracture and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.67