Trabectedin maintenance therapy after liposomal doxorubicin plus trabectedin combination in patients with relapsed ovarian cancer: the randomized, phase II TRAMANT study
The results suggest that TRB may be a viable maintenance option for patients with relapsed ovarian cancer, providing a sustained response with favorable tolerability. Nonetheless, the small sample size underscores the need for further research to validate these findings. Studies with larger cohorts are necessary to confirm these results and optimize treatment strategies for recurrent ovarian cancer.
Authors
- Valentina Tuninetti (ORCID: https://orcid.org/0000-0002-7377-0888)
- Claudio Zamagni (ORCID: https://orcid.org/0000-0003-0052-2581)
- Paolo Scollo (ORCID: https://orcid.org/0000-0001-6275-7488)
- Giovanni Scambia (ORCID: https://orcid.org/0000-0002-9503-9041)
- Carmine De Angelis (ORCID: https://orcid.org/0000-0003-1158-4630)
- Elena Geuna (ORCID: https://orcid.org/0000-0002-4290-058X)
- Giuseppe Scibilia (ORCID: https://orcid.org/0000-0002-1618-5391)
- Vanda Salutari (ORCID: https://orcid.org/0009-0007-1104-7866)
- Giuseppa Scandurra (ORCID: https://orcid.org/0000-0001-8025-581X)
- Antonio Ardizzoia (ORCID: https://orcid.org/0000-0003-2232-5677)
- Simona Scalone (ORCID: https://orcid.org/0000-0002-4647-0919)
- Giorgio Valabrega (ORCID: https://orcid.org/0000-0001-5444-6305)
- Valentina Lombardo (ORCID: https://orcid.org/0000-0002-0446-6436)
- Antonella Savarese (ORCID: https://orcid.org/0000-0003-0011-6276)
Institutions
- Università degli Studi di Enna Kore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Alessandro Manzoni Hospital (IT)
- Federico II University Hospital (IT)
- Azienda USL di Bologna (IT)
- Centro di Riferimento Oncologico (IT)
- A. O. Ordine Mauriziano di Torino (IT)
- National Cancer Institute (MY)
- Ospedale Cannizzaro (IT)
- Candiolo Cancer Institute (IT)
Publication Details
- Journal
- International Journal of Gynecological Cancer
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1016/j.ijgc.2025.101950
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00