Serum BDNF and progression to MCI in cognitively normal older adults: A prospective cohort study
These findings suggest a protective role of BDNF against clinical progression to MCI in cognitively healthy older individuals. This effect appears to be more prominent in women, as well as in relatively younger, less educated, and amyloid PET-negative individuals.
Authors
- Gijung Jung (ORCID: https://orcid.org/0000-0001-5952-3373)
- Bo Kyung Sohn (ORCID: https://orcid.org/0000-0002-1444-1099)
- Yun‐Sang Lee (ORCID: https://orcid.org/0000-0003-1640-2090)
- Min Soo Byun (ORCID: https://orcid.org/0000-0003-3159-4510)
- Hyejin Ahn (ORCID: https://orcid.org/0000-0002-6613-4680)
- Dahyun Yi (ORCID: https://orcid.org/0000-0002-0860-0946)
- Kyungtae Kim (ORCID: https://orcid.org/0000-0002-4325-5156)
- Kwangsik Nho (ORCID: https://orcid.org/0000-0002-7624-3872)
- Jun‐Young Lee (ORCID: https://orcid.org/0000-0002-5893-3124)
- Dong Young Lee (ORCID: https://orcid.org/0000-0001-8976-8320)
- Joon Hyung Jung
- Yoon‐Keun Kim (ORCID: https://orcid.org/0000-0001-7610-7654)
Institutions
- Seoul National University (KR)
- New Generation University College (ET)
- Seoul National University Hospital (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- Inje University Sanggye Paik Hospital (KR)
- National University College (PR)
- Chungbuk National University Hospital (KR)
- Indiana University – Purdue University Indianapolis (US)
- Naver (South Korea) (KR)
Publication Details
- Journal
- The Journal of Prevention of Alzheimer s Disease
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1016/j.tjpad.2025.100210
- Citations
- 2
- Primary Topic
- Nerve injury and regeneration
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Seoul National University
- Ministry of Science, ICT and Future Planning
- Ministry of Health and Welfare
- Korea Health Industry Development Institute
- Ministry of Science and ICT, South Korea
- National Institutes of Health