An Extremely Rare Case of Squamous Cell Carcinoma Following Treatment for External Auditory Canal Papilloma

The case is of a 60-year-old woman with a history of radiotherapy for parotid adenoid cystic carcinoma. Twenty years after irradiation, a papilloma developed in the left external auditory canal. Nine years after excision of the papilloma, a squamous cell carcinoma developed in the same region. This is a rare case of squamous cell carcinoma following treatment for a papilloma and is considered radiation-induced cancer. Because re-irradiation is not possible as a treatment for radiation-induced cancer, it is necessary to diagnose the cancer early so that curative resection is possible. Multiple biopsies should be considered when malignancy is suspected because a single biopsy may not be sufficient to diagnose an auditory canal tumor.

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Publication Details

Journal
Cureus
Published
2025-05-24
DOI
https://doi.org/10.7759/cureus.84755
Primary Topic
Ear and Head Tumors
Type
article
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0.00
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article

An Extremely Rare Case of Squamous Cell Carcinoma Following Treatment for External Auditory Canal Papilloma

T Sato, Hidenori Inohara, Yumi Ohta, Yoshiyuki Ozono et al.
Cureus
Ear and Head Tumors
article

An Extremely Rare Case of Squamous Cell Carcinoma Following Treatment for External Auditory Canal Papilloma

T Sato, Hidenori Inohara, Yumi Ohta, Yoshiyuki Ozono, Motoyuki Suzuki
article en

Abstract

The case is of a 60-year-old woman with a history of radiotherapy for parotid adenoid cystic carcinoma. Twenty years after irradiation, a papilloma developed in the left external auditory canal. Nine years after excision of the papilloma, a squamous cell carcinoma developed in the same region. This is a rare case of squamous cell carcinoma following treatment for a papilloma and is considered radiation-induced cancer. Because re-irradiation is not possible as a treatment for radiation-induced cancer, it is necessary to diagnose the cancer early so that curative resection is possible. Multiple biopsies should be considered when malignancy is suspected because a single biopsy may not be sufficient to diagnose an auditory canal tumor.

CureusVol. 17(5)
Osaka National Hospital (JP), The University of Osaka (JP)
Good health and well-being
Openalex Percentile: Top 83%
Ear and Head Tumors
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An Extremely Rare Case of Squamous Cell Carcinoma Following Treatment for External Auditory Canal Papilloma — T Sato, Hidenori Inohara, et al. · Cureus (2025) | TGRS Research Map | TGRS