Breast Carcinoma in a Nulliparous Woman: A Case Report

Breast carcinoma is a heterogeneous malignancy with multifactorial etiology involving genetic, hormonal, environmental, and reproductive factors. Nulliparity is a recognized risk factor due to prolonged exposure to unopposed endogenous estrogens. This case report presents a 42-year-old nulliparous female diagnosed with right-sided breast carcinoma, who presented with a palpable breast mass and ipsilateral axillary lymphadenopathy. Clinical examination and imaging revealed a well-defined, mobile lesion in the upper inner quadrant of the right breast, classified as BIRADS III. Given the tumor size and nodal involvement, a Modified Radical Mastectomy (MRM) was performed under general anesthesia. Histopathological and receptor status evaluation will guide further management, including adjuvant therapies. This case underscores the importance of recognizing nulliparity as a significant risk factor and highlights the need for individualized, multidisciplinary management strategies in breast cancer. Keywords: Nulliparity, Breast cancer, Mastectomy, Hormone exposure

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Publication Details

Journal
Journal of Biomedical and Pharmaceutical Research
Published
2025-05-23
DOI
https://doi.org/10.32553/jbpr.v14i3.1310
Primary Topic
Male Breast Health Studies
Type
article
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article

Breast Carcinoma in a Nulliparous Woman: A Case Report

M Lakshmi Madhuri, K. Vamshi Krishna, B. S. Suchithra, P. Santhoshimatha
Journal of Biomedical and Pharmaceutical Research
Male Breast Health Studies
article

Breast Carcinoma in a Nulliparous Woman: A Case Report

M Lakshmi Madhuri, K. Vamshi Krishna, B. S. Suchithra, P. Santhoshimatha
article en

Abstract

Breast carcinoma is a heterogeneous malignancy with multifactorial etiology involving genetic, hormonal, environmental, and reproductive factors. Nulliparity is a recognized risk factor due to prolonged exposure to unopposed endogenous estrogens. This case report presents a 42-year-old nulliparous female diagnosed with right-sided breast carcinoma, who presented with a palpable breast mass and ipsilateral axillary lymphadenopathy. Clinical examination and imaging revealed a well-defined, mobile lesion in the upper inner quadrant of the right breast, classified as BIRADS III. Given the tumor size and nodal involvement, a Modified Radical Mastectomy (MRM) was performed under general anesthesia. Histopathological and receptor status evaluation will guide further management, including adjuvant therapies. This case underscores the importance of recognizing nulliparity as a significant risk factor and highlights the need for individualized, multidisciplinary management strategies in breast cancer. Keywords: Nulliparity, Breast cancer, Mastectomy, Hormone exposure

Journal of Biomedical and Pharmaceutical ResearchVol. 14(3)
Advanced Numerical Research and Analysis Group (IN)
Openalex Percentile: Top 84%
Male Breast Health Studies
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