Viability and suitability of rat pup organotypic spinal cord slice cultures in a transection injury model
OSCs from P11 animals maintain viability comparable to P4 OSCs while also exhibiting a scarring response. This study concludes that P11 OSCs are a valid alternate to P4 OSC transection SCI model.
Authors
- Linda Howard (ORCID: https://orcid.org/0000-0003-4760-7996)
- Ciara Shortiss (ORCID: https://orcid.org/0000-0002-2936-3310)
- Siobhán S. McMahon (ORCID: https://orcid.org/0000-0002-6846-3605)
Institutions
- Ollscoil na Gaillimhe – University of Galway (IE)
- University Hospital Galway (IE)
- COPE Galway (IE)
Publication Details
- Journal
- Journal of Neuroscience Methods
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1016/j.jneumeth.2025.110499
- Primary Topic
- Anesthesia and Neurotoxicity Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Galway
- Irish Research Council
- College of Medicine, Nursing and Health Sciences, National University of Ireland, Galway