Unveiling the Masquerader: A Rare Case of Pigmented Erythroplasia of Queyrat With Successful Multimodal Treatment

Pigmented erythroplasia of Queyrat (EQ) is a rare variant of in situ squamous cell carcinoma that can clinically and dermoscopically mimic melanoma, which makes it hard to diagnose. We report the case of a 66-year-old man with a slowly progressive pigmented penile plaque. Dermoscopy and histology confirmed the diagnosis of pigmented EQ. The patient was successfully treated with photodynamic therapy followed by reconstructive surgery. This case highlights the importance of considering pigmented EQ in the differential diagnosis of genital pigmented lesions and illustrates the effectiveness of a conservative multimodal approach.