Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease

Our bioinformatics analysis and experimental results suggest that USP15 and CUL2 may contribute to the progression of COPD through ubiquitination modification. To our knowledge, this is the first study to demonstrate the involvement of USP15 and CUL2 in COPD. Our results may provide new insights into the diagnosis and treatment of COPD.

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Publication Details

Journal
Hereditas
Published
2025-05-24
DOI
https://doi.org/10.1186/s41065-025-00460-1
Citations
1
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
1.52
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article

Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease

Zhaoxiong Zhang, Shulei Sun, Haiyan Zhao
1 citations
Hereditas
Chronic Obstructive Pulmonary Disease (COPD) Research
1.52
article

Identification and validation of USP15 and CUL2 as ubiquitination related biomarker in chronic obstructive pulmonary disease

Zhaoxiong Zhang, Shulei Sun, Haiyan Zhao
article en
1 citations

Abstract

Our bioinformatics analysis and experimental results suggest that USP15 and CUL2 may contribute to the progression of COPD through ubiquitination modification. To our knowledge, this is the first study to demonstrate the involvement of USP15 and CUL2 in COPD. Our results may provide new insights into the diagnosis and treatment of COPD.

HereditasVol. 162(1)
Tianjin Medical University General Hospital (CN)
Good health and well-being
Openalex Percentile: Top 18%
Chronic Obstructive Pulmonary Disease (COPD) Research
1.52
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