A novel KRAS exon 2 drop-off digital PCR assay for mutation detection in cell-free DNA of cancer patients
We developed and clinically validated a highly accurate ddPCR drop-off assay for KRAS exon 2 hot-spot detection in cfDNA with broad applicability for clinic and research.
Authors
- Ralph Fritsch (ORCID: https://orcid.org/0000-0001-9639-3213)
- Achim Weber (ORCID: https://orcid.org/0000-0003-0073-3637)
- Martin Zoche (ORCID: https://orcid.org/0000-0002-0421-7229)
- T. Brezina
- Saskia Hussung (ORCID: https://orcid.org/0000-0001-7987-0065)
- Dilara Akhoundova (ORCID: https://orcid.org/0000-0003-1639-3059)
- Bianca Addamo-De Nard
- Meret Geissmann
- Clelia Pistoni
Institutions
- University of Bern (CH)
- University of Zurich (CH)
- University Hospital of Bern (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1186/s13000-025-01637-y
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Universitätsspital Zürich