Ocular and Periocular Leprosy Confirmed by Polymerase Chain Reaction and Histopathology with Therapeutic Insights

This case report thus provides evidence that Mycobacterium leprae can indeed penetrate the ocular coats despite a good immune response & Multi-Drug Therapy. Intravitreal injection Imipenem seems to be an effective drug choice in the management of Mycobacterium leprae endophthalmitis.

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Publication Details

Journal
Ocular Immunology and Inflammation
Published
2025-05-24
DOI
https://doi.org/10.1080/09273948.2025.2509719
Primary Topic
Leprosy Research and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Ocular and Periocular Leprosy Confirmed by Polymerase Chain Reaction and Histopathology with Therapeutic Insights

Santosh Ramesh, Shruthi Mysore Krishna, Madhusmita Das, Kavya Nagaraj et al.
Ocular Immunology and Inflammation
Leprosy Research and Treatment
article

Ocular and Periocular Leprosy Confirmed by Polymerase Chain Reaction and Histopathology with Therapeutic Insights

Santosh Ramesh, Shruthi Mysore Krishna, Madhusmita Das, Kavya Nagaraj, Nashra Alma, Smitha Kuthyar Shambu
article en

Abstract

This case report thus provides evidence that Mycobacterium leprae can indeed penetrate the ocular coats despite a good immune response & Multi-Drug Therapy. Intravitreal injection Imipenem seems to be an effective drug choice in the management of Mycobacterium leprae endophthalmitis.

Ocular Immunology and InflammationVol. 33(8)
L V Prasad Eye Institute (IN), Narayana Nethralaya (IN), Jyotirmay Eye Clinic (IN), Schieffelin Institute of Health Research and Leprosy Centre (IN)
Openalex Percentile: Top 85%
Leprosy Research and Treatment
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