Bifidobacterium ameliorates lupus nephritis and modulates aberrant differentiation of lymphocyte subsets
Bifidobacterium is significantly diminished in SLE patients, influencing kidney injury and immune cell balance in LN. Moreover, Bifidobacterium, its total metabolites and SCFAs' supplementation in MRL/lpr mice notably improved kidney damage and restored immune cell equilibrium in MRL/lpr mice.
Authors
- Xiangguo Duan (ORCID: https://orcid.org/0000-0003-1651-5757)
- Lihua Wu (ORCID: https://orcid.org/0000-0003-4505-0805)
- Zebing Guan
- Shuhong Chi (ORCID: https://orcid.org/0000-0003-1141-7605)
- Yanan Liu (ORCID: https://orcid.org/0000-0002-0091-7068)
- Xiaoyu Zhang (ORCID: https://orcid.org/0000-0002-2041-9955)
- Chunxia Su
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Lara D. Veeken
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1093/rheumatology/keaf271
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03