Unraveling drug resistance mechanisms in testicular cancer through immune cell phenotypes: a bidirectional Mendelian randomization analysis revealing novel therapeutic targets

Our findings reveal immune-related mechanisms underlying drug resistance in testicular cancer, offering potential targets for overcoming therapeutic resistance and guiding future treatment strategies.

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Publication Details

Journal
Discover Oncology
Published
2025-05-24
DOI
https://doi.org/10.1007/s12672-025-02757-z
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.00
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article

Unraveling drug resistance mechanisms in testicular cancer through immune cell phenotypes: a bidirectional Mendelian randomization analysis revealing novel therapeutic targets

Tianen Wu, Xiao Lin
1 links
Discover Oncology
Cancer-related molecular mechanisms research
article

Unraveling drug resistance mechanisms in testicular cancer through immune cell phenotypes: a bidirectional Mendelian randomization analysis revealing novel therapeutic targets

Tianen Wu, Xiao Lin
article en

Abstract

Our findings reveal immune-related mechanisms underlying drug resistance in testicular cancer, offering potential targets for overcoming therapeutic resistance and guiding future treatment strategies.

Discover OncologyVol. 16(1)
The 180th Hospital of PLA (CN)
Good health and well-being
Openalex Percentile: Top 84%
Cancer-related molecular mechanisms research
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