Estimate hazard ratios in small clinical trials without reported hazard ratios
This simple approach allows for the estimate of HRs from published KM curves in small survival studies without reported HRs, facilitating their inclusion in meta-analyses. This increases the overall sample size and enhances the reliability of synthesized clinical evidence.
Authors
- Ziwei Song (ORCID: https://orcid.org/0000-0002-5223-5034)
- Mingjie Wu (ORCID: https://orcid.org/0009-0000-2884-4019)
- Yuanjian Huang (ORCID: https://orcid.org/0000-0002-1611-8252)
- Shuyuan Wang (ORCID: https://orcid.org/0000-0001-9686-5022)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1007/s12672-025-02703-z
- Primary Topic
- Statistical Methods in Clinical Trials
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Government of Jiangsu Province
- Nanjing Medical University