[Analysis of Risk Factors for Meningeal Metastasis in Patients with Lung Adenocarcinoma Following Non-surgical Interventions].
Age at diagnosis, EGFR L858R mutation status, ALK gene mutation status, concurrent liver metastasis, globulin levels at baseline were significantly associated with the risk of developing MM in patients with LUAD patients who did not undergo surgical intervention. For patients diagnosed at a younger age, carrying the EGFR L858R mutation, or presenting with baseline liver metastasis, early implementation of tertiary prevention strategies for MM is crucial. Regular monitoring of MM status should be conducted in these high-risk groups.
Authors
- Jianlong Lin
- Jiyang Fu (ORCID: https://orcid.org/0000-0002-3971-6079)
- Sihui Wang (ORCID: https://orcid.org/0000-0003-4735-8934)
- Yanping Su (ORCID: https://orcid.org/0000-0002-0563-0082)
- Jing Li (ORCID: https://orcid.org/0009-0007-3236-9637)
- Yibo Wang (ORCID: https://orcid.org/0000-0001-9984-581X)
- Guojun Zhang (ORCID: https://orcid.org/0000-0003-1756-0082)
- Chunya Lu
- Nan Jiang (ORCID: https://orcid.org/0000-0002-7152-4034)
- Yun Yue (ORCID: https://orcid.org/0000-0002-5818-2236)
- Yuqing Ren (ORCID: https://orcid.org/0000-0002-2125-7695)
- Mengxue Kong
Institutions
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-04-20
- DOI
- https://doi.org/10.3779/j.issn.1009-3419.2025.101.06
- Primary Topic
- Brain Metastases and Treatment
- Type
- article