Fine-tuning predictive models: a comprehensive analysis for accurate diabetes risk stratification

Diabetes is a major global health concern since it causes serious complications like kidney disease, heart problems, and eyesight loss. In pursuit of accurate disease diagnosis machine learning (ML) methods have been employed resulting in favourable outcomes. In this study, an innovative diabetes prediction model is introduced that incorporates a comparison of various ML techniques, including logistic regression, K-nearest neighbour, naive Bayes, decision tree, and CatBoost on a diabetes database in order to improve on existing systems for disease prediction. The model is specifically concerned with diabetes by establishing the best performing model based on performance metrics such as accuracy, recall, precision, F1 score, Mathews correlation coefficient (MCC), Cohen Kappa, index of agreement and area under the curve (AUC). To optimise their results the techniques are subjected to hyperparameter tuning. The metric values thus obtained from the proposed methodology establish CatBoost as the best performing model and, hence, the most viable for diabetes prediction.

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Publication Details

Journal
International Journal of Bioinformatics Research and Applications
Published
2025-01-01
DOI
https://doi.org/10.1504/ijbra.2025.146351
Primary Topic
Cardiovascular Function and Risk Factors
Type
article
Field-Weighted Citation Impact
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article

Fine-tuning predictive models: a comprehensive analysis for accurate diabetes risk stratification

Inayat Ali, Nuzhat Ahmad Yatoo
International Journal of Bioinformatics Research and Applications
Cardiovascular Function and Risk Factors
article

Fine-tuning predictive models: a comprehensive analysis for accurate diabetes risk stratification

Inayat Ali, Nuzhat Ahmad Yatoo
article en

Abstract

Diabetes is a major global health concern since it causes serious complications like kidney disease, heart problems, and eyesight loss. In pursuit of accurate disease diagnosis machine learning (ML) methods have been employed resulting in favourable outcomes. In this study, an innovative diabetes prediction model is introduced that incorporates a comparison of various ML techniques, including logistic regression, K-nearest neighbour, naive Bayes, decision tree, and CatBoost on a diabetes database in order to improve on existing systems for disease prediction. The model is specifically concerned with diabetes by establishing the best performing model based on performance metrics such as accuracy, recall, precision, F1 score, Mathews correlation coefficient (MCC), Cohen Kappa, index of agreement and area under the curve (AUC). To optimise their results the techniques are subjected to hyperparameter tuning. The metric values thus obtained from the proposed methodology establish CatBoost as the best performing model and, hence, the most viable for diabetes prediction.

International Journal of Bioinformatics Research and ApplicationsVol. 21(3)
B.S. Abdur Rahman Crescent Institute of Science & Technology (IN)
Openalex Percentile: Top 79%
Cardiovascular Function and Risk Factors
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Fine-tuning predictive models: a comprehensive analysis for accurate diabetes risk stratification — Inayat Ali, Nuzhat Ahmad Yatoo · International Journal of Bioinformatics Research and Applications (2025) | TGRS Research Map | TGRS