Risk Factors and Prognostic Implications in Synchronous Breast-Thyroid Dual Primary Cancers: A Matched Case-Control Study
This first matched case-control analysis reveals that synchronous DBTMs represent a unique clinical subgroup with aggressive biological behavior. The identified triad of young age, ER positivity, and familial predisposition provides a risk stratification framework for dual-cancer screening and targeted surveillance strategies.
Authors
- Yantao Zhang (ORCID: https://orcid.org/0000-0002-6661-1133)
- Peng Zhang (ORCID: https://orcid.org/0000-0002-7259-881X)
- Tao Li (ORCID: https://orcid.org/0000-0002-3337-6202)
- Bin Lu (ORCID: https://orcid.org/0000-0001-7184-2211)
- Jun Qi (ORCID: https://orcid.org/0000-0002-4853-703X)
- Yong Sun
Institutions
- Jinan City People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/cmar.s505310
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00