Expression and Diagnostic Value of Nrf2 and p62 in Cervical Squamous Cell Carcinoma and Intraepithelial Lesions
Nrf2 and p62 are either not expressed or expressed at low levels in benign/reactive squamous epithelium, with expression increasing in LSIL, and being highest in HSIL and SCC. Both markers show a positive correlation across different cervical lesions, and either Nrf2 or p62 alone can effectively diagnose various cervical lesions, with even better diagnostic outcomes when used in combination.
Authors
- Wei Wei (ORCID: https://orcid.org/0000-0002-6244-3187)
- Qing Kai Han
- Xingyan Hu
Institutions
- Yichang Central People's Hospital (CN)
Publication Details
- Journal
- Cancer Management and Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/cmar.s513226
- Citations
- 1
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.81