Facile and Multicomponent Synthesis of Amino Pyrazole employed by Mg (NO3)2 As Catalyst

ABSTRACT: The right path of investigation in the present study, an efficient and cost-effective method for the preparation of derivatives of 5-Amino-1, 3-diaryl-1 H-pyrazole-4-carbonitriles using Phenyl hydrazine, substituted aromatic aldehyde, and malononitrile in acetonitrile as a solvent employing Mg(NO3)2 as a catalyst under solvent condition. The chemical structures of the titled compounds were confirmed by 1H-NMR &13CNMR, Mass spectral and Elemental analysis. Antimicrobial activities of the titled compounds were also examined by various strains and exhibited mild to moderate anti-bacterial activities. KEYWORDS: Aromatic aldehyde, Phenyl hydrazine, malononitrile, Amino Pyrazole, Mg(NO3)2 , anti-bacterial activities