Kidney function and cognitive aging and impairment among diverse Hispanic/Latino individuals: Study of Latinos‐Investigation of Neurocognitive Aging (HCHS/SOL)
Kidney disease has garnered increased attention in interpreting blood-based biomarkers of Alzheimer's disease and related disorders. Hispanic/Latino individuals are at increased risk for kidney disease. We found that urinary albumin-to-creatinine ratio outperformed estimated glomerular filtration in relation to cognitive function and impairment. Our findings suggest that kidney dysfunction is an independent marker of cognitive function and impairment.
Authors
- Nora Franceschini (ORCID: https://orcid.org/0009-0001-8346-3662)
- Freddie Márquez (ORCID: https://orcid.org/0000-0001-9916-9225)
- James Phillip Lash (ORCID: https://orcid.org/0000-0002-6580-4080)
- Douglas Galasko
- Hector M. González (ORCID: https://orcid.org/0000-0003-4867-7902)
- Wassim Tarraf (ORCID: https://orcid.org/0000-0001-8888-7918)
- Tali Elfassy (ORCID: https://orcid.org/0000-0002-7528-7988)
- Sayaka Kuwayama (ORCID: https://orcid.org/0009-0007-1526-1747)
- Natasha Z. Anita (ORCID: https://orcid.org/0009-0007-9179-1539)
- Tanya S. Johns (ORCID: https://orcid.org/0000-0001-9480-5990)
- Ariana M. Stickel (ORCID: https://orcid.org/0000-0002-6312-2377)
- Martha L. Daviglus (ORCID: https://orcid.org/0000-0002-6791-8727)
Institutions
- University of North Carolina at Chapel Hill (US)
- Albert Einstein College of Medicine (US)
- University of Miami (US)
- Wayne State University (US)
- San Diego State University (US)
- University of California San Diego (US)
- University of Illinois Chicago (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1002/alz.70301
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Office of Dietary Supplements
- University of Miami
- University of North Carolina
- Northwestern University
- San Diego State University
- Institut National Du Cancer
- National Institutes of Health
- University of Illinois at Urbana-Champaign
- Albert Einstein College of Medicine, Yeshiva University
- University of Illinois at Chicago
- National Institute on Aging
- National Heart, Lung, and Blood Institute
- National Institute on Deafness and Other Communication Disorders
- National Institute of Diabetes and Digestive and Kidney Diseases
- National Institute of Neurological Disorders and Stroke
- National Institute of Dental and Craniofacial Research
- National Institute on Minority Health and Health Disparities