Metabolic profiling of frailty, associations with type 2 diabetes and interaction with genetic susceptibility
The increased risk of T2D in individuals with frailty may be mediated through effects on the metabolome, and the influence of such metabolic alterations on diabetes risk may be amplified in individuals with genetic susceptibility to T2D.
Authors
- Yunfei Liao (ORCID: https://orcid.org/0000-0003-0688-775X)
- Hancheng Yu (ORCID: https://orcid.org/0000-0001-5214-3730)
- Rui Li (ORCID: https://orcid.org/0000-0002-8321-8026)
- Jinchi Xie
- Jun‐Xiang Chen (ORCID: https://orcid.org/0000-0001-8997-3439)
- Tingting Geng (ORCID: https://orcid.org/0000-0002-6220-3968)
- Jijuan Zhang (ORCID: https://orcid.org/0000-0002-2860-9673)
- Gang Liu (ORCID: https://orcid.org/0000-0003-4804-1787)
- Yue Li (ORCID: https://orcid.org/0000-0003-3747-1482)
- Yuxiang Wang (ORCID: https://orcid.org/0000-0002-0413-1660)
- Shuang Chen (ORCID: https://orcid.org/0000-0001-5254-6353)
- Lu Qi (ORCID: https://orcid.org/0000-0002-8041-7791)
- Hongyan Xu (ORCID: https://orcid.org/0000-0002-7777-1634)
- Xianli Li (ORCID: https://orcid.org/0009-0009-0087-3702)
- An Pan (ORCID: https://orcid.org/0000-0002-1089-7945)
Institutions
- Changchun University of Science and Technology (CN)
- Hubei Provincial Center for Disease Control and Prevention (CN)
- Wuhan Union Hospital (CN)
- Union Hospital (CN)
- Xiamen Medical College
- Huazhong University of Science and Technology (CN)
- Xiamen University of Technology (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1186/s12933-025-02776-8
- Citations
- 5
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 6.12
Funders
- National Natural Science Foundation of China