Cost-utility of computed tomography in patients with atypical chest pain clinically referred for invasive coronary angiography: randomised controlled trial
Question What is the cost-effectiveness of using CT compared to invasive coronary angiography (ICA) for diagnosing coronary artery disease in patients with atypical chest pain? Findings A CT-first diagnostic strategy was €1543 less costly per patient over a 3-year follow-up, yielding similar quality-adjusted life years compared to ICA. Clinical relevance CT offers a cost-effective, non-invasive alternative to ICA for patients with atypical chest pain, reducing healthcare costs significantly without compromising patient-reported outcomes or quality of life.
Authors
- Stefan Höfer (ORCID: https://orcid.org/0000-0002-6128-3687)
- Konrad Neumann (ORCID: https://orcid.org/0000-0001-9482-0971)
- Thomas Reinhold (ORCID: https://orcid.org/0000-0001-5169-7029)
- Henryk Dreger (ORCID: https://orcid.org/0000-0003-1909-4329)
- Valentin Brodszky (ORCID: https://orcid.org/0000-0002-6095-2295)
- Nina Rieckmann (ORCID: https://orcid.org/0000-0002-6870-451X)
- Alexander Mielke (ORCID: https://orcid.org/0000-0002-4583-3888)
- Marc Dewey (ORCID: https://orcid.org/0000-0002-4402-2733)
- Mahmoud Mohamed (ORCID: https://orcid.org/0000-0002-3077-5427)
- Maria Bosserdt
Institutions
- Innsbruck Medical University (AT)
- Corvinus University of Budapest (HU)
- Humboldt-Universität zu Berlin (DE)
- Deutsches Herzzentrum der Charité (DE)
- German Centre for Cardiovascular Research (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- European Radiology
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1007/s00330-025-11692-0
- Primary Topic
- Radiation Dose and Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft