Efficacy and safety evaluation of pulsed laser-activated injectable hydrogel for combined photodynamic and photothermal therapy in hypertrophic scar treatment

The ICG-HA hydrogel can effectively and safely synergize PDT and PTT to improve hypertrophic scar conditions under pulsed laser irradiation, especially single-pulse irradiation. This approach provides valuable reference for the clinical treatment in scar treatment.

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Publication Details

Journal
Photodiagnosis and Photodynamic Therapy
Published
2025-05-24
DOI
https://doi.org/10.1016/j.pdpdt.2025.104647
Primary Topic
Dermatologic Treatments and Research
Type
article
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article

Efficacy and safety evaluation of pulsed laser-activated injectable hydrogel for combined photodynamic and photothermal therapy in hypertrophic scar treatment

Chendong Ji, Xinling Zhang, Lu Han, Kun Zhang et al.
Photodiagnosis and Photodynamic Therapy
Dermatologic Treatments and Research
article

Efficacy and safety evaluation of pulsed laser-activated injectable hydrogel for combined photodynamic and photothermal therapy in hypertrophic scar treatment

Chendong Ji, Xinling Zhang, Lu Han, Kun Zhang, Yaqi Wei, Hongyi Zhao, Yi Zhang, Hongtao Chen, Xuejie Gao, Mengjuan Mu
article en

Abstract

The ICG-HA hydrogel can effectively and safely synergize PDT and PTT to improve hypertrophic scar conditions under pulsed laser irradiation, especially single-pulse irradiation. This approach provides valuable reference for the clinical treatment in scar treatment.

Photodiagnosis and Photodynamic TherapyVol. 54
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), NEC (China) (CN), Beijing University of Chemical Technology (CN)
Openalex Percentile: Top 79%
Dermatologic Treatments and Research
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