Circulating protein biomarkers and their association with vulnerable plaque characteristics – a PROSPECT II substudy

We were able to identify distinct biomarker patterns associated with PB and LCBI. IL-18R1 and CSF-1 had a strong relationship with PB. ANGPTL3 was associated with lipid rich plaques but not with PB, supporting its role in lipid accumulation and development of vulnerable plaques.

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Publication Details

Journal
International Journal of Cardiology Cardiovascular Risk and Prevention
Published
2025-05-24
DOI
https://doi.org/10.1016/j.ijcrp.2025.200440
Citations
2
Primary Topic
Protease and Inhibitor Mechanisms
Type
article
Field-Weighted Citation Impact
1.87

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article

Circulating protein biomarkers and their association with vulnerable plaque characteristics – a PROSPECT II substudy

Michael Mæng, Jonas Persson, Lars Kjøller‐Hansen, Ziad A. Ali et al.
2 citations
International Journal of Cardiology Cardiovascular Risk and Prevention
Protease and Inhibitor Mechanisms
1.87
article

Circulating protein biomarkers and their association with vulnerable plaque characteristics – a PROSPECT II substudy

Michael Mæng, Jonas Persson, Lars Kjøller‐Hansen, Ziad A. Ali, Ori Ben‐Yehuda, Tania Sharma, Ole Fröbert, Rune Wiseth, Thomas Engstrøm, Rebecca Tremain Rylance, Alf Inge Larsen, Stefan Karl James, David Erlinge, Akiko Maehara, Mitsuaki Matsumura, Gregg W. Stone, Sasha Koul, Gary S. Mintz
article en
2 citations

Abstract

We were able to identify distinct biomarker patterns associated with PB and LCBI. IL-18R1 and CSF-1 had a strong relationship with PB. ANGPTL3 was associated with lipid rich plaques but not with PB, supporting its role in lipid accumulation and development of vulnerable plaques.

International Journal of Cardiology Cardiovascular Risk and PreventionVol. 26
Uppsala University (SE), University of Copenhagen (DK), Karolinska University Hospital (SE), NewYork–Presbyterian Hospital (US), Lund University (SE), Cardiovascular Institute of the South (US), Örebro University (SE), Stavanger University Hospital (NO), New York Hospital Queens (US), Aarhus University Hospital (DK), Rigshospitalet (DK), Karolinska Institutet (SE), University of California San Diego (US), Zealand University Hospital (DK), St Olav's University Hospital (NO), Cardiovascular Research Foundation (US), Columbia University (US), Icahn School of Medicine at Mount Sinai (US)
Hjärt-Lungfonden, Vetenskapsrådet
Openalex Percentile: Top 14%
Protease and Inhibitor Mechanisms
1.87
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