Enhancing menaquinone‐7 biosynthesis by optimized fermentation strategies and fed‐batch cultivation of food‐derived <i>Bacillus subtilis</i>
The current study developed a strain with good safety and antibiotic sensitivity for producing MK-7, and improved its biosynthesis through optimized fermentation strategies and scaling up the process, laying the foundation for the availability of biologically active MK-7 fermented food in the food industry. © 2025 Society of Chemical Industry.
Authors
- Siyu Xue
- Yingxi Chen (ORCID: https://orcid.org/0000-0002-3565-1052)
- Naihui Dong (ORCID: https://orcid.org/0000-0002-7937-1562)
- Yujiao Zhang (ORCID: https://orcid.org/0000-0002-3794-2697)
- Sufang Zhang (ORCID: https://orcid.org/0009-0009-0264-0742)
- Hui Guo (ORCID: https://orcid.org/0009-0006-3820-9549)
- Yiwei Dai (ORCID: https://orcid.org/0000-0001-7600-249X)
Institutions
- Dalian Polytechnic University (CN)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1002/jsfa.14320
- Citations
- 1
- Primary Topic
- Vitamin K Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.12
Funders
- National Natural Science Foundation of China