Examining the Impact of Age on Chemotherapy Effectiveness among Lung Cancer Patients

Introduction: Lung cancer remains a prevalent type of cancer that affects many people and causes their death. Variations in chemotherapy effectiveness among different age groups of lung cancer patients can influence treatment outcomes, necessitating an investigation into age-specific responses to chemotherapy. The research aims to examine the impact of age on chemotherapy effectiveness among lung cancer (LC) patients, focusing on overall survival time, response rate, and comorbidity scores across different age categories.Methods: A total of 300 lung cancer patients undergoing chemotherapy were surveyed. Patients were divided into three age groups: ≤ 50 years, 50–69 years, and ≥ 70 years. Data analysis was performed using SPSS 25, employing descriptive statistics, regression analysis, correlation analysis, and ANOVA to evaluate factors affecting chemotherapy outcomes.Result: Descriptive statistics revealed the highest average survival time of 36 months with a response rate of 90%. Regression analysis identified an intercept of 62.00, with negative coefficients associated with increasing age and advanced disease stage. Correlation analysis showed a positive correlation of 0.45 between response rate and survival time. ANOVA indicated an average response rate of 67.8% among patients aged below 50, suggesting a potential benefit in tailored treatment strategies for younger patients. Conclusion: These results support the treatment of patients with lung cancer, according to their age in an attempt to improve the outcomes of chemotherapy sessions. The research highlights a need for further research into age-related factors that influence treatment outcomes, emphasizing personalized approaches for improved patient care.

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Journal
Health Leadership and Quality of Life
Published
2025-05-20
DOI
https://doi.org/10.56294/hl2025603
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
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article

Examining the Impact of Age on Chemotherapy Effectiveness among Lung Cancer Patients

V Vasanthi, Parthkumar Devmurari, Renuka Devi MR, Lakshya Swarup et al.
Health Leadership and Quality of Life
Lung Cancer Treatments and Mutations
article

Examining the Impact of Age on Chemotherapy Effectiveness among Lung Cancer Patients

V Vasanthi, Parthkumar Devmurari, Renuka Devi MR, Lakshya Swarup, Lokesh Verma, V. Swathi
article en

Abstract

Introduction: Lung cancer remains a prevalent type of cancer that affects many people and causes their death. Variations in chemotherapy effectiveness among different age groups of lung cancer patients can influence treatment outcomes, necessitating an investigation into age-specific responses to chemotherapy. The research aims to examine the impact of age on chemotherapy effectiveness among lung cancer (LC) patients, focusing on overall survival time, response rate, and comorbidity scores across different age categories.Methods: A total of 300 lung cancer patients undergoing chemotherapy were surveyed. Patients were divided into three age groups: ≤ 50 years, 50–69 years, and ≥ 70 years. Data analysis was performed using SPSS 25, employing descriptive statistics, regression analysis, correlation analysis, and ANOVA to evaluate factors affecting chemotherapy outcomes.Result: Descriptive statistics revealed the highest average survival time of 36 months with a response rate of 90%. Regression analysis identified an intercept of 62.00, with negative coefficients associated with increasing age and advanced disease stage. Correlation analysis showed a positive correlation of 0.45 between response rate and survival time. ANOVA indicated an average response rate of 67.8% among patients aged below 50, suggesting a potential benefit in tailored treatment strategies for younger patients. Conclusion: These results support the treatment of patients with lung cancer, according to their age in an attempt to improve the outcomes of chemotherapy sessions. The research highlights a need for further research into age-related factors that influence treatment outcomes, emphasizing personalized approaches for improved patient care.

Health Leadership and Quality of LifeVol. 4
Physiotherapy New Zealand (NZ), Advanced Numerical Research and Analysis Group (IN), Sri Balaji Vidyapeeth University (IN), Sree Balaji Dental College and Hospital (IN), Mahatma Gandhi Medical College and Research Institute (IN), Chitkara University (IN)
Openalex Percentile: Top 81%
Lung Cancer Treatments and Mutations
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