Identification of α2-macroglobulin as a biomarker for type 2 diabetes in human serum
Serum a2-MG levels are elevated in obese individuals and those with T2DM. It shows high sensitivity and specificity for predicting obesity and T2DM, suggesting its potential as a biomarker for T2DM diagnosis. However, further large-scale studies are needed to confirm its clinical utility.
Authors
- Zhaoli Yan (ORCID: https://orcid.org/0000-0002-5379-804X)
- Yoosoo Chang (ORCID: https://orcid.org/0000-0002-6945-9050)
- Limei He
- Ming-Jie Wang (ORCID: https://orcid.org/0000-0001-8217-348X)
Institutions
- Inner Mongolia People's Hospital (CN)
- Hohhot First Hospital (CN)
- Inner Mongolia Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.3389/fendo.2025.1534490
- Citations
- 1
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.35
Funders
- Natural Science Foundation of Inner Mongolia