Current Treatment Challenge for Neonatal Sepsis

Background & Aim: Probiotics have been known to modulate the immune system and help reduce the risk of infections in infants. This study aims to investigate the impact of probiotics on term babies' health parameters. However, their effectiveness in term babies is still under investigation. Results: A total of 170 cases were analyzed and reported in the study, focusing on the relationship between probiotics and neonatal sepsis in infants under 28 days old. The analysis involved examining the efficacy of probiotic supplementation in reducing the risk of neonatal sepsis. Parameters such as neutrophil count, CRP levels, and the duration of hospital stay exhibit notable variations between the two groups. However, no significant differences are observed in platelet count and WBC, ultimately indicating the therapeutic efficacy of probiotics. Conclusion: The findings suggest that probiotics may have a beneficial role in enhancing certain health outcomes in term babies. The significant differences in neutrophil count, CRP levels, and hospital stay duration evidences this. Further research is needed to understand the mechanisms underlying these effects and to optimize probiotic interventions in this population.