Evaluation of Hepatoprotective Potential of Zizyphus xylopyrus Extract

The present study was carried out to evaluate the hepatoprotective activity of selected plant by paracetamol induced liver injury, which are indigenous to Indian region. Zizyphus xylopyrus (Z. xylopyrus) is used traditionally in the treatment of variety of diseases such as obesity, urinary troubles, diabetes, skin infections, fever, diarrhoea, insomnia and digestive disorder. Ethanobotanical survey shows that various parts of plant have been used in the treatment of diseases by folk person. The aerial and root barks, leaves, and fruits of Zizyphus species used in Indian system of medicine for the treatment of various diseases such as weakness, liver complaints, obesity, diabetes, skin infections, fever, diarrhoea, insomnia and digestive disorders. It is used in Pyorrhoea and to check oogenesis. The bark is used for its astringent activity and as dental sticks for teeth cleaning. In different parts of India this plant is also used in the treatment of diarrhoea. The present work emphasizes the evaluation of hepatoprotective activity Zizyphus xylopyrus roots. The result revealed that methanolic extracts of plant could be useful in preventing paracetamol induced liver injury.