Teaching Reform in Biopharmaceutical Specialty Based on CDIO Concept

本研究以CDIO (构思–设计–实现–运作)工程教育理念为指导，针对生物制药专业教学中存在的课程体系偏理论化、实践平台薄弱、校企协同不足等问题，提出系统性教学改革方案。重构“理论–实践–项目”三位一体的模块化课程群，将GMP规范、生物反应器设计、药物质量控制等核心内容融入项目驱动式教学；建立虚拟仿真与实体实验结合的实践平台，引入企业真实案例与生产标准，强化学生工程设计及问题解决能力；同时改革评价体系，构建涵盖过程性考核、企业参与的多维评价机制，并推进“双师型”师资队伍建设与校企协同育人机制。改革预期实现学生工程思维、创新能力与职业素养的全面提升，促进产学研深度融合，为生物制药行业输送高素质应用型人才提供实践参考。Guided by the CDIO (Conceive, Design, Implement, Operate) engineering education concept, this study proposes a systematic teaching reform plan to address issues in biopharmaceutical specialty teaching, such as a theoretical curriculum system, a weak practical platform, and insufficient school-enterprise collaboration. By reconstructing the modular curriculum group of “theory-practice-project” trinity, core contents such as GMP specification, bioreactor design, and drug quality control are integrated into project-driven teaching. A practical platform combining virtual simulation and physical experiments is established, introducing real cases and production standards from enterprises to enhance students’ engineering design and problem-solving abilities. Additionally, the evaluation system is reformed to create a multi-dimensional evaluation mechanism encompassing process assessment and enterprise participation, and to promote the development of “double-qualified” teaching staff and a school-enterprise collaborative education mechanism. The reform aims to comprehensively enhance students’ engineering thinking, innovation ability, and professional qualities, foster deeper integration of production, teaching, and research, and provide practical references for cultivating high-quality applied talents in the biopharmaceutical industry.