Genomic characterisation of the first case of IMP-13-producing carbapenem-resistant Pseudomonas aeruginosa ST313/ExoU+/O1 isolate in Chile

This study provides the first genomic characterization of an IMP-13-producing ST313 carbapenem-resistant P. aeruginosa isolate (150UDEC/24) in Chile, containing multiple resistance genes and the ExoU virulence factor. Phylogenetic analysis suggests unique evolution, emphasizing the need for continued genomic surveillance to monitor the emergence of highly resistant, virulent strains in clinical settings.

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Publication Details

Journal
Journal of Global Antimicrobial Resistance
Published
2025-05-23
DOI
https://doi.org/10.1016/j.jgar.2025.05.016
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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article

Genomic characterisation of the first case of IMP-13-producing carbapenem-resistant Pseudomonas aeruginosa ST313/ExoU+/O1 isolate in Chile

Sergio Mella, Andrés Opazo-Capurro, Alejandro Aguayo-Reyes, Mario Quezada-Aguiluz et al.
Journal of Global Antimicrobial Resistance
Antibiotic Resistance in Bacteria
article

Genomic characterisation of the first case of IMP-13-producing carbapenem-resistant Pseudomonas aeruginosa ST313/ExoU+/O1 isolate in Chile

Sergio Mella, Andrés Opazo-Capurro, Alejandro Aguayo-Reyes, Mario Quezada-Aguiluz, Gerardo González‐Rocha, Maximiliano Matus-Köhler, Pablo Araya-Vega, Néstor Herrera-Chávez, Felipe Morales-León
article en

Abstract

This study provides the first genomic characterization of an IMP-13-producing ST313 carbapenem-resistant P. aeruginosa isolate (150UDEC/24) in Chile, containing multiple resistance genes and the ExoU virulence factor. Phylogenetic analysis suggests unique evolution, emphasizing the need for continued genomic surveillance to monitor the emergence of highly resistant, virulent strains in clinical settings.

Journal of Global Antimicrobial ResistanceVol. 44
University of Concepción (CL), Hospital Regional de Concepción (CL)
Openalex Percentile: Top 91%
Antibiotic Resistance in Bacteria
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Genomic characterisation of the first case of IMP-13-producing carbapenem-resistant Pseudomonas aeruginosa ST313/ExoU+/O1 isolate in Chile — Sergio Mella, Andrés Opazo-Capurro, et al. · Journal of Global Antimicrobial Resistance (2025) | TGRS Research Map | TGRS