Visible-light-catalyzed decarboxylation of aryl acetic acids for the construction of aromatic aldehydes

We have developed a novel strategy for the synthesis of aromatic aldehyde compounds through a visible-light-catalyzed decarboxylation oxidation reaction under mild conditions. Notably, the current protocol tolerates a variety of functional groups, and the aromatic aldehyde products are easily derivatized to other valuable functional building blocks.

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Publication Details

Journal
Organic & Biomolecular Chemistry
Published
2025-01-01
DOI
https://doi.org/10.1039/d5ob00704f
Primary Topic
Radical Photochemical Reactions
Type
article
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article

Visible-light-catalyzed decarboxylation of aryl acetic acids for the construction of aromatic aldehydes

Biao Nie, Yunfei Yuan, J Wang, Haisheng Xie et al.
Organic & Biomolecular Chemistry
Radical Photochemical Reactions
article

Visible-light-catalyzed decarboxylation of aryl acetic acids for the construction of aromatic aldehydes

Biao Nie, Yunfei Yuan, J Wang, Haisheng Xie, Xiaonan Luo, Zhibing Liang, Lusheng Liao, Yanmei Wen
article en

Abstract

We have developed a novel strategy for the synthesis of aromatic aldehyde compounds through a visible-light-catalyzed decarboxylation oxidation reaction under mild conditions. Notably, the current protocol tolerates a variety of functional groups, and the aromatic aldehyde products are easily derivatized to other valuable functional building blocks.

Organic & Biomolecular ChemistryVol. 23(25)
Chinese Academy of Tropical Agricultural Sciences (CN), Beijing Botanical Garden (CN), HEC Pharm (China) (CN), South China Botanical Garden (CN), Guangdong Ocean University (CN)
Clean water and sanitation
Openalex Percentile: Top 91%
Radical Photochemical Reactions
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