The double-edged sword of metabolic and bariatric surgery: extending the biliary limb can trigger bacterial translocation, sepsis, and liver inflammation – an experimental study
Mortality in longer biliary limb MBS surgery is caused by bacterial overgrowth, translocation, and gut-liver axis inflammation, which were reversed by oral gut decontamination with antibiotics.
Authors
- Sander Lefere (ORCID: https://orcid.org/0000-0001-5734-3467)
- Anja M. Geerts (ORCID: https://orcid.org/0000-0002-2218-9081)
- Xavier Verhelst (ORCID: https://orcid.org/0000-0002-2798-5415)
- Anneleen Heldens
- Tom Van de Wiele (ORCID: https://orcid.org/0000-0001-6854-5689)
- Louis Onghena (ORCID: https://orcid.org/0000-0002-8516-4834)
- Yves Van Nieuwenhove (ORCID: https://orcid.org/0000-0003-3064-5638)
- Lindsey Devisscher (ORCID: https://orcid.org/0000-0003-4862-9580)
- Hans Van Vlierberghe (ORCID: https://orcid.org/0000-0003-0647-9238)
- Sarah Raevens (ORCID: https://orcid.org/0000-0003-2810-7507)
- Milton Antwi (ORCID: https://orcid.org/0000-0001-8831-073X)
- Anne Hoorens
- Kim De Paepe (ORCID: https://orcid.org/0000-0002-7948-6765)
Institutions
- Ghent University Hospital (BE)
- Ghent University (BE)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1097/js9.0000000000002502
- Citations
- 3
- Primary Topic
- Bariatric Surgery and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 6.02
Funders
- Universitair Ziekenhuis Gent
- Universiteit Gent