Erdheim-Chester with central nervous system involvement: Complex histopathological diagnosis and neurosurgical challenges in a rare histiocytic disorder

This case highlights the strategic utility of the "one-and-a-half " frontotemporal craniotomy in the resection of complex supratentorial lesions. It also underscores the critical importance of molecular diagnostics, particularly the identification of the BRAF V600E mutation, in guiding treatment decisions in ECD.

Authors

Publication Details

Journal
Surgical Neurology International
Published
2025-05-23
DOI
https://doi.org/10.25259/sni_199_2025
Primary Topic
Histiocytic Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Erdheim-Chester with central nervous system involvement: Complex histopathological diagnosis and neurosurgical challenges in a rare histiocytic disorder

Marco Antonio Rodríguez-Florido, Luis Guillermo Castellanos-Pallares, Kevin S. Toache, Santiago Puentes-Rosero et al.
Surgical Neurology International
Histiocytic Disorders and Treatments
article

Erdheim-Chester with central nervous system involvement: Complex histopathological diagnosis and neurosurgical challenges in a rare histiocytic disorder

Marco Antonio Rodríguez-Florido, Luis Guillermo Castellanos-Pallares, Kevin S. Toache, Santiago Puentes-Rosero, Massiel Zenteno-Zenteno, Pedro Adrian Gonzalez-Zavala
article en

Abstract

This case highlights the strategic utility of the "one-and-a-half " frontotemporal craniotomy in the resection of complex supratentorial lesions. It also underscores the critical importance of molecular diagnostics, particularly the identification of the BRAF V600E mutation, in guiding treatment decisions in ECD.

Surgical Neurology InternationalVol. 16
Openalex Percentile: Top 85%
Histiocytic Disorders and Treatments
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