Research Progress on the Neurodevelopmental Outcomes of Twins

双胞胎易出现神经系统发育障碍以及心理行为问题，这可能与双胎妊娠中的合并症或其他生物因素密切相关，如早产、绒毛膜的性质、宫内生长受限、辅助生殖技术、分娩方式等。随着辅助生殖技术的不断成熟与应用，双胞胎出生率显著上升，其神经系统发育结局引起广泛关注。本文对双胞胎神经发育结局、早期预测方法和相关影响因素的研究进展进行综述。Twins are susceptible to neurological developmental disorders, as well as psychological and behavioral issues, which may be related to the presence of comorbidities during twin pregnancies or other biological factors, including but not limited to preterm birth, chorionicity, intrauterine growth restriction, the utilization of assisted reproductive technology, and the mode of delivery. As assisted reproductive technology has matured and its application has increased, there has been a corresponding surge in the incidence of twin births and its nervous system development outcome has attracted wide attention. This article provides a review of the research progress on the neurodevelopmental outcomes, early prediction methods and related influencing factors in twins.