Milk sialyl-oligosaccharides mediate the early colonization of gut commensal microbes in piglets
Our findings reveal the influence of sialyl-oligosaccharides in promoting microbial diversity and gut homeostasis, thereby highlighting the importance of sialic acid as a key factor in shaping milk-driven microbial colonization during the early stages of piglet development. Video Abstract.
Authors
- Julio Villena (ORCID: https://orcid.org/0000-0003-4941-4960)
- Keita Nishiyama (ORCID: https://orcid.org/0000-0001-6483-0669)
- Eri Nakazaki
- Seigi Tsuchida
- Itsuko Fukuda (ORCID: https://orcid.org/0000-0001-5969-4295)
- Tomonori Nochi (ORCID: https://orcid.org/0000-0003-1800-6972)
- Eri Nishiyama (ORCID: https://orcid.org/0000-0002-1158-0456)
- Yuta Sugiyama (ORCID: https://orcid.org/0000-0002-8929-0854)
- Wakako Ikeda‐Ohtsubo (ORCID: https://orcid.org/0000-0001-8489-1936)
- Fu Namai (ORCID: https://orcid.org/0000-0002-2939-4934)
- R. Hashimoto
- Sudeb Saha (ORCID: https://orcid.org/0000-0002-9163-3801)
- Haruki Kitazawa (ORCID: https://orcid.org/0000-0003-4586-5553)
- Kenji Okano (ORCID: https://orcid.org/0000-0002-9112-3211)
- Yoshihito Suda
- Eita Toyoshi
- Ryusuke Ohgi
- Kasumi Suzuki (ORCID: https://orcid.org/0000-0001-7917-7842)
- Takao Mukai
- Taiga Sakuma
- Mutsumi Furukawa
- Gou YOSHIOKA
- Takafumi Shanoh
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Gunma University (JP)
- Tohoku University (JP)
- Kyowa Kirin (Japan) (JP)
- Miyagi University (JP)
- Centro Científico Tecnológico - Tucumán (AR)
- Gifu Prefectural Research Institute for Forests (JP)
- Kansai University (JP)
- Kitasato University (JP)
- Kobe University (JP)
Publication Details
- Journal
- Microbiome
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1186/s40168-025-02129-3
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Japan Society for the Promotion of Science