Single-cell RNA sequencing and traditional RNA sequencing reveals the role of cancer-associated fibroblasts in head and neck squamous cell carcinomas cohort
Our study provides a novel CAF-based prognostic model and nomogram for predicting patient outcomes in HNSC. These findings highlight the importance of CAFs in the tumor microenvironment and their potential as therapeutic and prognostic biomarkers.
Authors
- Yixin Qiao (ORCID: https://orcid.org/0000-0001-6387-3130)
- Yangju Fu
- Ling Zhong (ORCID: https://orcid.org/0000-0003-3657-4092)
- Shasha He (ORCID: https://orcid.org/0000-0002-7464-7793)
- Jian Zou (ORCID: https://orcid.org/0000-0002-7779-1467)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.1007/s12672-025-02507-1
- Citations
- 1
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81