Comparative analysis of the performance of the large language models ChatGPT-3.5, ChatGPT-4 and Open AI-o1 in the field of Programmed Cell Death in myeloma

Open AI-o1 outperforms ChatGPT-3.5 and ChatGPT-4 in accuracy, depth, and reliability when addressing complex clinical questions related to Programmed Cell Death in multiple myeloma. Its advanced "thinking" ability facilitates comprehensive and evidence-based responses, making it a more dependable tool for clinical decision support. These findings suggest that Open AI-o1 holds significant potential for enhancing clinical practices in specialized oncological fields, though ongoing validation and integration with human expertise remain essential.

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Publication Details

Journal
Discover Oncology
Published
2025-05-23
DOI
https://doi.org/10.1007/s12672-025-02648-3
Citations
1
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
1.77
Controls
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article

Comparative analysis of the performance of the large language models ChatGPT-3.5, ChatGPT-4 and Open AI-o1 in the field of Programmed Cell Death in myeloma

Shan Luo, Bo Nie, Tao Bo, Yanhong Li et al.
1 citations
Discover Oncology
Multiple Myeloma Research and Treatments
1.77
article

Comparative analysis of the performance of the large language models ChatGPT-3.5, ChatGPT-4 and Open AI-o1 in the field of Programmed Cell Death in myeloma

Shan Luo, Bo Nie, Tao Bo, Yanhong Li, Yun Zeng, Wu Kun, Li Yuntao, Cheng Shenju, Shi Mingxia
article en
1 citations

Abstract

Open AI-o1 outperforms ChatGPT-3.5 and ChatGPT-4 in accuracy, depth, and reliability when addressing complex clinical questions related to Programmed Cell Death in multiple myeloma. Its advanced "thinking" ability facilitates comprehensive and evidence-based responses, making it a more dependable tool for clinical decision support. These findings suggest that Open AI-o1 holds significant potential for enhancing clinical practices in specialized oncological fields, though ongoing validation and integration with human expertise remain essential.

Discover OncologyVol. 16(1)
Kunming Medical University (CN), First Affiliated Hospital of Kunming Medical University (CN)
Peace, Justice and strong institutions
Openalex Percentile: Top 16%
Multiple Myeloma Research and Treatments
1.77
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